Cilian

Description

Cilnidipine is a dihydropyridine calcium channel blocker with action on both N- and L-type calcium channels used to treat hypertension.

Generic Name

Cilnidipine

Indication

Cilnidipine is indicated for the management of hypertension for end-organ protection.5 It is reported to be useful in elderly patients and in those with diabetes and albuminuria. Cilnidipine has been increasingly used in patients with chronic kidney disease Hypertension is the term used to describe the presence of high blood pressure. The blood pressure is generated by the force of the blood pumped from the heart against the blood vessels. Thus hypertension is caused when there is too much pressure on the blood vessels and this effect can damage the blood vessel

Mechanism of action

Cilnidipine acts on the L-type calcium channels of blood vessels by blocking the incoming calcium and suppressing the contraction of blood vessels, thereby reducing blood pressure. Cilnidipine also works on the N-type calcium channel located at the end of the sympathetic nerve, inhibiting the emission of norepinephrine and suppressing the increase in stress blood pressure

Precautions

Cilnidipine should be used with caution in patients with hypotension (low blood pressure), heart failure and poor cardiac reserve. Cilnidipine should be discontinued in patients who feel chest pain following the administration of the drug. Sudden withdrawal of the drug to be avoided as this may exacerbate angina.

Storage

Store the medicine in a tightly closed container at room temperature. Protect from excess heat and light. Keep out of reach of children.

Packing

1X10